Though the meaning of five letters of myō, hō, ren, ge, and kyō is interpreted differently depending on the commentators and teachers, they are all based on provisional sūtras, so that none of them is correct. However, Bodhisattva Nāgārjuna writes in his Great Wisdom Discourse, “The wonder of the Lotus Sūtra is like a great pharmacist making medicine out of poison.” I believe this interpretation shows that he grasped the meaning of the character myō. The poison in this case means the truth of suffering in this life and the truth regarding the cause of suffering (evil passions and karma in previous existences). Thus, the cause and effect of life and death is the poison of poison. The Lotus Sūtra preaches that the illusions of life and death at once become Nirvana, and the illusions of evil passions are equal to enlightenment. This means that the poison was changed into excellent medicine due to the ultimate teaching of myō. Excellent medicine refers to the one made of poison.

Ōta-dono Nyōbō Gohenji, A Response to the Wife of Lord Ōta, Writings of Nichiren Shōnin, Faith and Practice, Volume 4, Page 167