Day 21 covers all of Chapter 16, The Duration of the Life of the Tathāgata.

Having last month considered the Buddha’s nirvana, we consider the Parable of the Skillful Physician and His Sick Children

“I will tell you a parable. There was once an excellent and wise physician. He was good at dispensing medicines and curing diseases. He had many sons, numbering ten, twenty, or a hundred. [One day] he went to a remote country on business. After he left home, the sons took poison. The poison passed into their bodies, and the sons writhed in agony, rolling on the ground. At that time the father returned home. Some sons had already lost their right minds while the others still had not. All the sons saw their father in the distance and had great joy. They begged him on their knees, saying, ‘You came back safely. We were ignorant. We took poison by mistake. Cure us, and give us back our lives!’

“Seeing his sons suffering so much, the father consulted books of prescriptions, and collected good herbs. having a good color, smell and taste. He compounded a medicine by pounding and sieving the herbs, and gave it to them, saying, ‘This is a very good medicine. It has good color, smell and taste. Take it! It will remove the pain at once and you will not suffer any more.’

“The sons who had not lost their right minds saw that this good medicine had a good color and smell, took it at once, and were cured completely. But the sons who had already lost their right minds did not consent to take the medicine given to them, although they rejoiced at seeing their father come home and asked him to cure them, because they were so perverted that they did not believe that this medicine having a good color and smell had a good taste.

The Daily Dharma offers this:

The children who had not lost their right minds saw that this good medicine had a good color and smell, took it at once, and were cured completely. But the children who had already lost their right minds did not consent to take the medicine given to them, although they rejoiced at seeing their father come home and asked him to cure them, because they were so perverted that they did not believe that this medicine having a good color and smell had a good taste.

In Chapter Sixteen of the Lotus Sūtra, the Buddha tells a parable of a wise physician who prepares medicine for his children who have accidentally poisoned themselves. He compares the children to us whose minds are poisoned by the delusions of greed, anger and ignorance. He also compares himself to the wise father and the medicine to the Lotus Sūtra that he has left for us. Until the children took the medicine and tasted it for themselves, they could not be cured of the poison. Until we make this practice of the Wonderful Dharma an active part of our lives, we cannot be cured of our delusions.

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